Document Detail

Catheter ablation of atrial fibrillation. -State of the Art-.
MedLine Citation:
PMID:  21914963     Owner:  NLM     Status:  MEDLINE    
Atrial fibrillation (AF) is an arrhythmia associated with increased morbidity and mortality. Since the first report of catheter ablation curing AF, numerous techniques have evolved, from linear ablation to segmental pulmonary vein (PV) isolation, to extensive encircling PV isolation, to left atrial (LA) linear ablation, to ablation of complex fragmented atrial electrograms (CFAEs) and ablation of ganglionated plexi. A new approach for complete isolation of the posterior LA, including all PVs, is box isolation. PV isolation is associated with a high clinical success rate in paroxysmal AF. However, in persistent AF or longstanding persistent AF, PV isolation only may not be sufficient, so additional ablation at sites with CFAEs is needed to improve the clinical outcome. A hybrid approach of combining PV isolation plus CFAE ablation is highly effective in the majority of patients with persistent AF or longstanding persistent AF. Thus, AF ablation is an effective and established treatment for AF that offers an excellent chance of a lasting cure. It is about time that AF ablation became a first-line therapy for selected patients with AF.
Koichiro Kumagai
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Publication Detail:
Type:  Journal Article; Review     Date:  2011-09-13
Journal Detail:
Title:  Circulation journal : official journal of the Japanese Circulation Society     Volume:  75     ISSN:  1347-4820     ISO Abbreviation:  Circ. J.     Publication Date:  2011  
Date Detail:
Created Date:  2011-09-22     Completed Date:  2012-03-13     Revised Date:  2012-12-19    
Medline Journal Info:
Nlm Unique ID:  101137683     Medline TA:  Circ J     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  2305-11     Citation Subset:  IM    
Heart Rhythm Center, Fukuoka Sanno Hospital, Fukuoka, Japan.
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MeSH Terms
Atrial Fibrillation / surgery*
Catheter Ablation / methods*
Pulmonary Veins
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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