Document Detail

Catecholamines in urine after death.
MedLine Citation:
PMID:  10464938     Owner:  NLM     Status:  MEDLINE    
Noradrenaline, adrenaline and dopamine levels were measured using high-performance liquid chromatography (HPLC) and electrochemical detection and related to urine creatinine in 30 specimens from unselected autopsies. Values calculated from patients with essential hypertension were used as a reference and raised values of noradrenaline, adrenaline and dopamine were found in 76.6, 80 and 23.3%, respectively. Using the Mann-Whitney U test, there was no difference between the 11 patients with myocardial infarction and the seven who died from severe head injury or multiple trauma. The median values in mmol/mol creatinine for patients with myocardial infarction and trauma were 0.07 and 0.12 for noradrenaline and 0.012 and 0.024 for adrenaline, respectively. Physiological stress is common before death and urine noradrenaline values at autopsy overlap those found in some normal subjects and at autopsy in patients with phaeochromocytoma.
W P Tormey; M Carney; R J FitzGerald
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Forensic science international     Volume:  103     ISSN:  0379-0738     ISO Abbreviation:  Forensic Sci. Int.     Publication Date:  1999 Jul 
Date Detail:
Created Date:  1999-09-28     Completed Date:  1999-09-28     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7902034     Medline TA:  Forensic Sci Int     Country:  IRELAND    
Other Details:
Languages:  eng     Pagination:  67-71     Citation Subset:  IM    
Department of Chemical Pathology, Beaumont Hospital, Dublin, Ireland.
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MeSH Terms
Aged, 80 and over
Catecholamines / urine*
Cause of Death
Chromatography, High Pressure Liquid
Creatinine / urine
Middle Aged
Pheochromocytoma / urine
Reference Values
Statistics, Nonparametric
Stress, Physiological / physiopathology
Reg. No./Substance:
0/Catecholamines; 60-27-5/Creatinine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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