Document Detail

Catecholamines in critical care.
MedLine Citation:
PMID:  3332227     Owner:  NLM     Status:  MEDLINE    
Catecholamines (norepinephrine, epinephrine, and dopamine) are released into circulation in response to stress and injury and as part of the body's attempt at vasoregulation in response to circulatory failure. Norepinephrine is released from sympathetic nerve terminal, and epinephrine and dopamine are released from the adrenal medulla. Plasma levels of these catecholamines have been reported to be elevated in various clinical settings: congestive heart failure, myocardial infarction, cardiopulmonary bypass, diabetic ketoacidosis, hypoxia, hemorrhage, and septic shock. These amines have both beneficial and detrimental effects on survival. Both norepinephrine and dopamine are often employed in the critically ill to selectively increase cardiocerebral and renal blood flow, respectively.
M Maddens; J Sowers
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Critical care clinics     Volume:  3     ISSN:  0749-0704     ISO Abbreviation:  Crit Care Clin     Publication Date:  1987 Oct 
Date Detail:
Created Date:  1988-11-22     Completed Date:  1988-11-22     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8507720     Medline TA:  Crit Care Clin     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  871-82     Citation Subset:  IM    
Wayne State University, Detroit, Michigan.
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MeSH Terms
Asthma / drug therapy,  metabolism
Catecholamines* / metabolism,  pharmacology,  therapeutic use
Critical Care*
Heart Failure / drug therapy,  metabolism
Myocardial Infarction / drug therapy,  metabolism
Shock, Hemorrhagic / drug therapy,  metabolism
Shock, Septic / drug therapy,  metabolism
Reg. No./Substance:

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