Document Detail

Catecholamines and blood pressure regulation.
MedLine Citation:
PMID:  2104398     Owner:  NLM     Status:  MEDLINE    
Catecholamines (CAs) play a central role in the regulation of blood pressure. Sympathetic adrenal effects are ultimately elicited by the neurotransmitter norepinephrine and the hormone epinephrine. Their release is under the control of higher centers and is finely modulated by several factors such as presynaptic receptors. Recent evidences suggest that also the peripheral dopaminergic system can participate in blood pressure regulation intervening in the blood flow regulation of some regions, and in sodium-water balance. The measurement of CAs in biological fluids has greatly enhanced our knowledge on the mechanisms regulating blood pressure and is widely applied in cardiovascular research. Clinical applications of CA measurement are still limited to the diagnosis of pheochromocytoma and to the differential diagnosis of hypotensive syndromes.
M Mannelli; C Pupilli; R Lanzillotti; L Ianni; M Serio
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Hormone research     Volume:  34     ISSN:  0301-0163     ISO Abbreviation:  Horm. Res.     Publication Date:  1990  
Date Detail:
Created Date:  1991-10-24     Completed Date:  1991-10-24     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0366126     Medline TA:  Horm Res     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  156-60     Citation Subset:  IM    
Endocrinology Service, University of Florence, Italy.
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MeSH Terms
Adrenal Gland Neoplasms / diagnosis
Adrenal Glands / metabolism
Autonomic Nervous System / physiology
Blood Pressure / physiology*
Catechol O-Methyltransferase / physiology
Catecholamines / physiology*
Hypotension / diagnosis
Monoamine Oxidase / physiology
Pheochromocytoma / diagnosis
Reg. No./Substance:
0/Catecholamines; EC Oxidase; EC O-Methyltransferase

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