Document Detail

Catecholamine-storing cells at acupuncture points of rabbits.
MedLine Citation:
PMID:  20633459     Owner:  NLM     Status:  MEDLINE    
Recent studies have shown that specific sites of the skin related to the acupoints contain a high concentration of catecholamines, especially noradrenaline (NA). Considering this newly discovered property of the acupoints we assumed that heterogeneous distribution of cutaneous catecholamines could be associated with a specific location of catecholamine-storing cells in acupoint sites. In the present work we used an immunohistochemical method and confocal laser scanning microscopy to examine the presence of catecholamine-storing cells at acupoints of rabbits. Double immunofluorescence staining with antibodies against adrenaline and NA revealed only the cells storing NA in the dermal layer of rabbit skin. NA-storing cells were randomly scattered as single cells as well as existing in small clusters in a globular tissue formation surrounded by blood vessels and capillaries. Microscopic analysis of histological sections also revealed that the distribution of NA-storing cells was closely associated with the location of acupoints. Thus results from our study strongly suggest that acupoint areas of rabbit skin contain catecholamine-storing cells which can release a high level of NA during acupuncture stimulation.
Vyacheslav Ogay; Min Su Kim; Hyo Jun Seok; Cheon Joo Choi; Kwang-Sup Soh
Related Documents :
11003689 - Control of cell ph in the t84 colon cell line.
3595179 - Sodium and bicarbonate fluxes in regenerating rabbit corneal endothelium.
20692299 - Further studies on the effects of intracrine and extracellular angiotensin ii on the re...
2782869 - Comparison of vibrio parahaemolyticus grown in estuarine water and rich medium.
1326409 - Ion transport in colon cancer cell cultures studied by x-ray microanalysis.
12060589 - Expression and function of sodium transporters in two opossum kidney cell clonal sublines.
16663929 - Conversion and distribution of cobalamin in euglena gracilis z, with special reference ...
18354169 - Glucose uptake is limiting in t cell activation and requires cd28-mediated akt-dependen...
22230969 - Quantitative and dynamic assay of single cell chemotaxis.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of acupuncture and meridian studies     Volume:  1     ISSN:  2093-8152     ISO Abbreviation:  J Acupunct Meridian Stud     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2010-07-16     Completed Date:  2010-09-17     Revised Date:  2012-08-08    
Medline Journal Info:
Nlm Unique ID:  101490763     Medline TA:  J Acupunct Meridian Stud     Country:  Korea (South)    
Other Details:
Languages:  eng     Pagination:  83-90     Citation Subset:  IM    
Biomedical Physics Laboratory, Department of Physics and Astronomy, Seoul National University, Seoul, Korea.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Acupuncture Points*
Catecholamines / metabolism*
Cells / metabolism*
Models, Animal
Skin / cytology*,  metabolism
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Clinical effectiveness of laser acupuncture: a systematic review.
Next Document:  Changes in electrical skin resistance at gallbladder 34 (GB34).