Document Detail


Catecholamine-storing cells at acupuncture points of rabbits.
MedLine Citation:
PMID:  20633459     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Recent studies have shown that specific sites of the skin related to the acupoints contain a high concentration of catecholamines, especially noradrenaline (NA). Considering this newly discovered property of the acupoints we assumed that heterogeneous distribution of cutaneous catecholamines could be associated with a specific location of catecholamine-storing cells in acupoint sites. In the present work we used an immunohistochemical method and confocal laser scanning microscopy to examine the presence of catecholamine-storing cells at acupoints of rabbits. Double immunofluorescence staining with antibodies against adrenaline and NA revealed only the cells storing NA in the dermal layer of rabbit skin. NA-storing cells were randomly scattered as single cells as well as existing in small clusters in a globular tissue formation surrounded by blood vessels and capillaries. Microscopic analysis of histological sections also revealed that the distribution of NA-storing cells was closely associated with the location of acupoints. Thus results from our study strongly suggest that acupoint areas of rabbit skin contain catecholamine-storing cells which can release a high level of NA during acupuncture stimulation.
Authors:
Vyacheslav Ogay; Min Su Kim; Hyo Jun Seok; Cheon Joo Choi; Kwang-Sup Soh
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of acupuncture and meridian studies     Volume:  1     ISSN:  2093-8152     ISO Abbreviation:  J Acupunct Meridian Stud     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2010-07-16     Completed Date:  2010-09-17     Revised Date:  2012-08-08    
Medline Journal Info:
Nlm Unique ID:  101490763     Medline TA:  J Acupunct Meridian Stud     Country:  Korea (South)    
Other Details:
Languages:  eng     Pagination:  83-90     Citation Subset:  IM    
Affiliation:
Biomedical Physics Laboratory, Department of Physics and Astronomy, Seoul National University, Seoul, Korea.
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MeSH Terms
Descriptor/Qualifier:
Acupuncture Points*
Animals
Catecholamines / metabolism*
Cells / metabolism*
Female
Models, Animal
Rabbits
Skin / cytology*,  metabolism
Chemical
Reg. No./Substance:
0/Catecholamines

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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