| Catecholamine release in the newborn infant at birth. | |
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MedLine Citation:
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PMID: 887309 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Catecholamines were determined by a fluorimetric technique in umbilical blood which was collected from newborn infants immediately after birth. The mean catecholamine concentration was 62.1 nmol/liter in the umbilical artery and 29.3 nmol/liter in the umbilical vein of newborn full term infants delivered uneventfully. This value is considerably higher than in resting adults. Similar levels of catecholamines were seen after elective cesarean sections, whereas considerably higher levels were found after breech deliveries. In the full term asphyxiated infants about a 4-fold increase of the catecholamine concentration was found in both the umbilical arterial and venous blood. The amine concentration level correlated inversely to the pH below 7.25 (10 log catecholamine concentration versus pH, r = -0.71). Preterm infants had, in general, lower amine levels than full term infants both after uneventful deliveries and after intrauterine asphyxia. The catecholamine levels were considerably increased in the newborn infants who showed some kind of abnormal fetal heart rate variation during the last hour before birth; in particular baseline changes were associated with high levels whereas only a moderate increase was seen after loss of beat-to-beat variation. |
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Authors:
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H Lagercrantz; P Bistoletti |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Pediatric research Volume: 11 ISSN: 0031-3998 ISO Abbreviation: Pediatr. Res. Publication Date: 1977 Aug |
Date Detail:
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Created Date: 1977-09-22 Completed Date: 1977-09-22 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0100714 Medline TA: Pediatr Res Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 889-93 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Apgar Score Asphyxia Neonatorum / blood Breech Presentation Catecholamines / blood* Cesarean Section Epinephrine / blood Female Fetal Blood / analysis* Gestational Age Heart Rate Humans Infant, Newborn* Infant, Premature Labor, Obstetric* Pregnancy Sympathetic Nervous System / physiology |
| Chemical | |
Reg. No./Substance:
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0/Catecholamines; 51-43-4/Epinephrine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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