Document Detail

Catatonia: a review.
MedLine Citation:
PMID:  18568581     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: To write an up-to-date review paper on catatonia using published literature. METHODS: This review involved a search using the terms "catatonia," "stupor," "catatonic schizophrenia" and "catalepsy" in the Cochrane Database of Systematic Reviews, the Medline database and EMBASE and PsychINFO. Additional use was made of these databases in searching for randomized controlled trials, meta-analyses, cohort studies, case-control studies, case series, case reports and reviews. RESULTS: Available evidence indicates that catatonia is a common neuropsychiatric syndrome characterized by the presence of various motor signs and symptoms. The underlying pathophysiologic-mechanisms points to a heterogeneous group of etiologies. Current classifications are based on the type of presentation and the duration of symptoms; agitated versus retarded and acute versus chronic. Available data supports the efficacy of benzodiazepines and electroconvulsive therapy (ECT) in the treatment of this condition, but the treatment response is limited by the chronicity of symptoms. CONCLUSIONS: Catatonia is a common disorder that occurs in a wide variety of psychiatric, neurological and medical conditions. At the current time, there is sufficient evidence to consider it as a specific nosologic syndrome with different subtypes and treatment responses.
Natalie D Weder; Sunanda Muralee; Heath Penland; Rajesh R Tampi
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists     Volume:  20     ISSN:  1547-3325     ISO Abbreviation:  Ann Clin Psychiatry     Publication Date:    2008 Apr-Jun
Date Detail:
Created Date:  2008-06-23     Completed Date:  2008-07-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8911021     Medline TA:  Ann Clin Psychiatry     Country:  United States    
Other Details:
Languages:  eng     Pagination:  97-107     Citation Subset:  IM    
Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06519, USA.
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MeSH Terms
Catatonia* / classification,  diagnosis,  drug therapy,  etiology
Grant Support
1 K01 HP 00071-03//PHS HHS

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