| Catatonia as a risk factor for the development of neuroleptic malignant syndrome: report of a case following treatment with clozapine. | |
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MedLine Citation:
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PMID: 19673089 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Catatonia is characterized by the predominance of psychomotor abnormalities and shares many clinical, biological and treatment response features with the neuroleptic malignant syndrome (NMS), a rare adverse reaction to psychoactive medications. It has been advocated that the two conditions should be placed along the same spectrum of disorders. A case of a 49-year-old woman, who developed NMS while on low dose clozapine soon after recovering from catatonia, is presented. The potential relationship between catatonia and NMS is discussed in the light of the existing literature, and attention is drawn to the risk for clozapine-induced NMS in catatonic patients. |
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Authors:
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Thomas Paparrigopoulos; Elias Tzavellas; Panagiotis Ferentinos; Iraklis Mourikis; John Liappas |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry Volume: 10 ISSN: 1562-2975 ISO Abbreviation: World J. Biol. Psychiatry Publication Date: 2009 |
Date Detail:
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Created Date: 2009-08-12 Completed Date: 2009-08-19 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101120023 Medline TA: World J Biol Psychiatry Country: England |
Other Details:
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Languages: eng Pagination: 70-3 Citation Subset: IM |
Affiliation:
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Department of Psychiatry, Athens University Medical School, Eginition Hospital, Athens, Greece. Thomas.Paparrigopoulos@iop.kcl.ac.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Antipsychotic Agents
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adverse effects*,
therapeutic use Catatonia / chemically induced, diagnosis, drug therapy* Clozapine / adverse effects*, therapeutic use Dose-Response Relationship, Drug Female Humans Middle Aged Neuroleptic Malignant Syndrome / diagnosis, etiology* Psychotic Disorders / drug therapy Risk Factors Schizophrenia, Catatonic / drug therapy |
| Chemical | |
Reg. No./Substance:
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0/Antipsychotic Agents; 5786-21-0/Clozapine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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