| Catatonia and its treatment. | |
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MedLine Citation:
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PMID: 19969591 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Psychiatric diagnoses are currently categorized on a syndromic basis. The syndrome of catatonia, however, remains in a diagnostic limbo, acknowledged predominantly as a subtype of schizophrenia. Yet, catatonia is present in about 10% of acutely ill psychiatry patients, only a minority of whom have schizophrenia. Among those with comorbid affective disorders, who comprise the largest subgroup of catatonic patients, the catatonic signs typically resolve dramatically and completely with benzodiazepine therapy. Those with schizophrenia respond less reliably, suggesting that the underlying processes causing the catatonia may be different in this group. The majority of patients with catatonia have concurrent psychosis. Failure to treat the catatonia before institution of antipsychotic medication may increase the risk of inducing neuroleptic malignant syndrome. At this point of time, the pathobiology of catatonia is unknown; the major reason for considering catatonia as a separate diagnostic entity would be to increase recognition of this eminently treatable neuropsychiatric syndrome. |
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Authors:
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Patricia I Rosebush; Michael F Mazurek |
Publication Detail:
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Type: Comment; Journal Article; Review Date: 2009-12-07 |
Journal Detail:
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Title: Schizophrenia bulletin Volume: 36 ISSN: 1745-1701 ISO Abbreviation: Schizophr Bull Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-03-08 Completed Date: 2010-06-02 Revised Date: 2011-07-25 |
Medline Journal Info:
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Nlm Unique ID: 0236760 Medline TA: Schizophr Bull Country: United States |
Other Details:
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Languages: eng Pagination: 239-42 Citation Subset: IM |
Affiliation:
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Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario L8P 3B6, Canada. Rosebush@HHSC.CA |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antipsychotic Agents
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adverse effects,
therapeutic use Benzodiazepines / adverse effects, therapeutic use* Catatonia / diagnosis, drug therapy*, psychology Combined Modality Therapy Drug Therapy, Combination Electroconvulsive Therapy Humans Neuroleptic Malignant Syndrome / prevention & control Schizophrenia, Catatonic / diagnosis, drug therapy*, psychology Syndrome |
| Chemical | |
Reg. No./Substance:
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0/Antipsychotic Agents; 12794-10-4/Benzodiazepines |
| Comments/Corrections | |
Comment On:
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Schizophr Bull. 2010 Mar;36(2):314-20
[PMID:
19586994
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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