Document Detail


Catastrophic rapid onset heparin-induced thrombocytopenia--victim of our own success.
MedLine Citation:
PMID:  20306898     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Heparin is integral to the treatment of acute coronary syndromes, deep vein thrombosis and its prophylaxis. An undesirable result of recurrent heparin use is rapid onset heparin-induced thrombocytopenia (HIT) within hours of exposure. This catastrophic condition is frequently diagnosed too late for therapy to be effective. We describe a case of fatal rapid onset HIT, analyze current evidence to diagnose this condition and propose a way so that it can be prevented.
Authors:
Sudip Nanda; Shree Gopal Sharma; Santo Longo
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta cardiologica     Volume:  65     ISSN:  0001-5385     ISO Abbreviation:  Acta Cardiol     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-03-23     Completed Date:  2010-04-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370570     Medline TA:  Acta Cardiol     Country:  Belgium    
Other Details:
Languages:  eng     Pagination:  93-5     Citation Subset:  IM    
Affiliation:
Dept of Internal Medicine, St.Luke's Hospital, Bethlehem, Pennsylvania 18015, USA. sudipnanda2000@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Adult
Anticoagulants / adverse effects*,  therapeutic use
Diagnosis, Differential
Disease Progression
Fatal Outcome
Follow-Up Studies
Heparin / adverse effects*,  therapeutic use
Humans
Male
Platelet Count
Thrombocytopenia / chemically induced*,  diagnosis
Thromboembolism / drug therapy
Time Factors
Chemical
Reg. No./Substance:
0/Anticoagulants; 9005-49-6/Heparin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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