Document Detail


Catastrophic antiphospholipid antibody syndrome in a young woman in the postpartum period.
MedLine Citation:
PMID:  21186706     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
A 27-year-old Hispanic female was admitted to hospital with fever, a sudden marked decrease in vision, and multi-organ failure shortly after preterm delivery by cesarean section for eclampsia. Her past history was significant for a spontaneous first trimester abortion and one live birth complicated by intrauterine growth retardation. She was found to have several focal brain infarcts, exudative retinal detachment, bilateral adrenal hemorrhage, renal insufficiency, hypertension and subsequently hypotension. Positive anticardiolipin antibodies, lupus anticoagulant, and anti-B2 glycoprotein-I, as well as deranged coagulation profile and PTT mixing studies aided in the diagnosis of catastrophic antiphospholipid antibody syndrome. Anticoagulation and high-dose intravenous steroids led to significant improvement in the patient's condition, including her vision.
Authors:
Tatiana B Jacobson; Victor O Kolade; Avni S Kapadia
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Tennessee medicine : journal of the Tennessee Medical Association     Volume:  103     ISSN:  1088-6222     ISO Abbreviation:  Tenn Med     Publication Date:    2010 Nov-Dec
Date Detail:
Created Date:  2010-12-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9609310     Medline TA:  Tenn Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  35-6, 39     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, University of Tennessee College of Medicine, Chattanooga 37403, USA.
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