| Catamnestic investigations in children with congenital hydrocephalus. | |
| | |
MedLine Citation:
|
PMID: 2375184 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Catamnestic investigations on the course of pregnancy, family history and genetics were carried out in 141 children suffering from congenital hydrocephalus. The results were compared with those obtained from a group of non-malformed controls investigated by the same criteria. There was a considerably higher incidence of pregnancy disturbances (i.e. diseases, drugs, haemorrhage etc.) in mothers who later gave birth to a child with congenital hydrocephalus, than mothers of the control group (congenital hydrocephalus: 61.3% vs. controls: 30.1%). This high incidence of pregnancy disturbances could be particularly referred to a sevenfold increased rate of diseases and a fourfold increased rate of drug intake during the first trimester. There was also a higher rate of malformed relatives in children with congenital hydrocephalus (16.7%) than in controls (6.4%); not only were malformations of the central nervous system found to be increased but also malformations of other organ systems in relatives. This is interpreted as a hint not only at genetic influences but also at a generally higher incidence of malformations in a relatively small group of persons. Calculated figures of recurrence risk were in accordance with empirical data used in genetic counselling. |
| | |
Authors:
|
T A Angerpointner; L Pockrandt; K Schroer |
Related Documents
:
|
12237634 - Substance abuse and polyhydramnios. 19695914 - Effect of maternal asthma, inhaled glucocorticoids and cigarette use during pregnancy o... 11724104 - Fda labeling system for drugs in pregnancy. 2260334 - Increased 6-hydroxycortisol excretion in pregnant women: implication of drug-metabolizi... 20511374 - Increases in urinary creatinine and blood pressure during early pregnancy in pre-eclamp... 7225294 - The effect of protamine on serum levels of placental protein 5 (pp5) in normal and abno... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Zeitschrift für Kinderchirurgie : organ der Deutschen, der Schweizerischen und der Osterreichischen Gesellschaft für Kinderchirurgie = Surgery in infancy and childhood Volume: 45 ISSN: 0174-3082 ISO Abbreviation: Z Kinderchir Publication Date: 1990 Jun |
Date Detail:
|
Created Date: 1990-08-27 Completed Date: 1990-08-27 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 8103794 Medline TA: Z Kinderchir Country: GERMANY, WEST |
Other Details:
|
Languages: eng Pagination: 151-5 Citation Subset: IM |
Affiliation:
|
Paediatric Surgical Clinic, Dr. von Haunersches Kinderspital of the University of Munich, F.R.G. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Abnormalities, Multiple Birth Weight Child, Preschool Diseases in Twins Drug Therapy / adverse effects Female Follow-Up Studies Gestational Age Humans Hydrocephalus / etiology*, genetics, surgery Infant, Newborn Male Maternal Age Paternal Age Pregnancy Pregnancy Complications / etiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Plasma concentrations of lidocaine and prilocaine and analgesic effect after dermal application of E...
Next Document: Myohyperplasia of the lung arterioles in congenital diaphragmatic defects