| Catalysis by the nucleolytic ribozymes. | |
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MedLine Citation:
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PMID: 21428954 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The nucleolytic ribozymes use general acid-base catalysis to contribute significantly to their rate enhancement. The VS (Varkud satellite) ribozyme uses a guanine and an adenine nucleobase as general base and acid respectively in the cleavage reaction. The hairpin ribozyme is probably closely similar, while the remaining nucleolytic ribozymes provide some interesting contrasts. |
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Authors:
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David M J Lilley |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Biochemical Society transactions Volume: 39 ISSN: 1470-8752 ISO Abbreviation: Biochem. Soc. Trans. Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-03-24 Completed Date: 2011-07-01 Revised Date: 2011-10-27 |
Medline Journal Info:
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Nlm Unique ID: 7506897 Medline TA: Biochem Soc Trans Country: England |
Other Details:
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Languages: eng Pagination: 641-6 Citation Subset: IM |
Affiliation:
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Cancer Research UK Nucleic Acid Structure Research Group, MSI/WTB Complex, University of Dundee, Dow Street, Dundee DD1 5EH, UK. d.m.j.lilley@dundee.ac.uk |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Catalysis Humans Hydrogen-Ion Concentration Hydrolysis Models, Biological Models, Molecular Nucleotides / metabolism* RNA, Catalytic / metabolism* |
| Grant Support | |
ID/Acronym/Agency:
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//Cancer Research UK |
| Chemical | |
Reg. No./Substance:
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0/Nucleotides; 0/RNA, Catalytic |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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