Document Detail

Catalase in the stratum corneum of patients with polymorphic light eruption.
MedLine Citation:
PMID:  9779248     Owner:  NLM     Status:  MEDLINE    
UV radiation generates reactive oxygen species, which may be involved in polymorphic light eruption. The endogenous enzymatic defense system includes catalase in the epidermis. Thirteen patients with a history of polymorphic light eruption, but free from lesions, and 13 controls were investigated from November to March. Catalase was analysed in the upper horny layer according to Colin et al.'s spectrophotometric technique. In polymorphic light eruption, catalase values were about 30% lower than in control subjects. Such deficiency was observed in patients free from the disease and not recently sun-exposed. The diminished skin catalase in irradiated polymorphic light eruption makes it possible that a longer restoration time of catalase is involved in the pathogenesis.
M Guarrera; P Ferrari; A Rebora
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta dermato-venereologica     Volume:  78     ISSN:  0001-5555     ISO Abbreviation:  Acta Derm. Venereol.     Publication Date:  1998 Sep 
Date Detail:
Created Date:  1998-12-02     Completed Date:  1998-12-02     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370310     Medline TA:  Acta Derm Venereol     Country:  NORWAY    
Other Details:
Languages:  eng     Pagination:  335-6     Citation Subset:  IM    
Department of Dermatology, University of Genoa, Italy.
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MeSH Terms
Catalase / metabolism*
Epidermis / enzymology*,  pathology
Middle Aged
Photosensitivity Disorders / enzymology*
Skin / enzymology,  pathology
Reg. No./Substance:

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