Document Detail


Catabolism of desialylated glycoproteins during carcinogenesis and inflammation in rats.
MedLine Citation:
PMID:  7324699     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Experiments were performed on rats injected with a malignant hepatoma (evoked by aflatoxin B1) or with inflammation induced by turpentine injection. On the 4th or 8th day after the injection, the following determinations were made: concentration of seromucoid, haptoglobin, sialic acid and fucose in blood serum; binding of asialo-glycoproteins by liver extracts; elimination of asialo-[125I]haptoglobin and asialo-[125I]orosomucoid from circulation. It was found that hepatoma and inflammation affected neither the activity of liver receptors for asialo-glycoproteins, nor the rate of asialo-glycoprotein elimination from circulation.
Authors:
J Osada; B Zawirska; J Chorazyczewski; W Dobryszycka
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta biochimica Polonica     Volume:  28     ISSN:  0001-527X     ISO Abbreviation:  Acta Biochim. Pol.     Publication Date:  1981  
Date Detail:
Created Date:  1982-03-13     Completed Date:  1982-03-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  14520300R     Medline TA:  Acta Biochim Pol     Country:  POLAND    
Other Details:
Languages:  eng     Pagination:  147-56     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Asialoglycoproteins
Female
Glycoproteins / metabolism*
Haptoglobins / metabolism
Inflammation / metabolism*
Liver / metabolism
Liver Neoplasms, Experimental / metabolism
Male
Neoplasms / metabolism*
Orosomucoid / metabolism
Rats
Chemical
Reg. No./Substance:
0/Asialoglycoproteins; 0/Glycoproteins; 0/Haptoglobins; 0/Orosomucoid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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