Document Detail

Cat scratch disease: a bacterial infection.
MedLine Citation:
PMID:  6612349     Owner:  NLM     Status:  MEDLINE    
Histopathologic examination of lymph nodes from 39 patients with clinical and pathological criteria for cat scratch disease revealed delicate pleomorphic Gram-negative bacilli in 34 of the 39 nodes. They were within the walls of capillaries in or near areas of follicular hyperplasia and within microabscesses. They were best seen with the Warthin-Starry silver impregnation stain. Organisms in lymph node sections exposed to convalescent serum from three patients and to immunoperoxidase stained equally well with all three samples. The organisms did not react with hyperimmune sera to Legionella pneumophila nor to several species of Rickettsia. These bacilli appear to be the causative agents of cat scratch disease.
D J Wear; A M Margileth; T L Hadfield; G W Fischer; C J Schlagel; F M King
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Science (New York, N.Y.)     Volume:  221     ISSN:  0036-8075     ISO Abbreviation:  Science     Publication Date:  1983 Sep 
Date Detail:
Created Date:  1983-10-28     Completed Date:  1983-10-28     Revised Date:  2007-03-19    
Medline Journal Info:
Nlm Unique ID:  0404511     Medline TA:  Science     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1403-5     Citation Subset:  IM    
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MeSH Terms
Cat-Scratch Disease / microbiology*,  pathology
Lymph Nodes / microbiology*,  pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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