Document Detail


Cassava root diet induces low pyruvate levels.
MedLine Citation:
PMID:  20462383     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The high cyanogenic-glucoside carbohydrate of the cassava root (Manihot esculenta) has special properties that make it an ideal therapeutic food for lowering nicotinamide adenine dinucleotide reduced form (NADH) and inducing Sirtuin (Sirt) gene overexpression when eaten in an exclusive mono-food diet regime. The author, using himself as the sole test subject, repeatedly induced low pyruvate levels (reflective of NADH levels) after being on the diet for 1-2 weeks at a time. The possible influences of exclusive cassava dieting on redox control and Sirtuin activation will be discussed.
Authors:
Van K Golay
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Rejuvenation research     Volume:  13     ISSN:  1557-8577     ISO Abbreviation:  Rejuvenation Res     Publication Date:    2010 Apr-Jun
Date Detail:
Created Date:  2010-05-13     Completed Date:  2010-08-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101213381     Medline TA:  Rejuvenation Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  260-1     Citation Subset:  IM    
Affiliation:
vkgolay@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Animals
Diet*
Down-Regulation
Humans
Manihot / chemistry,  physiology*
Oxidation-Reduction / drug effects
Plant Extracts / pharmacology
Plant Roots / chemistry,  physiology*
Pyruvic Acid / blood*,  metabolism
Sirtuins / genetics,  metabolism
Chemical
Reg. No./Substance:
0/Plant Extracts; 127-17-3/Pyruvic Acid; EC 3.5.1.-/Sirtuins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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