Document Detail

Case selection for cardiac resynchronization in atrial fibrillation.
MedLine Citation:
PMID:  24054479     Owner:  NLM     Status:  In-Data-Review    
Remarkably little evidence exists that cardiac resynchronization therapy (CRT) is effective in patients who have atrial fibrillation (AF) but who otherwise seem suitable for this treatment. The landmark trials of CRT generally excluded patients with AF because atrioventricular (AV) resynchronization was considered a possibly important mechanism by which CRT might deliver its benefits. The only landmark trial that included many patients with AF confirmed marked benefit among patients in sinus rhythm but no benefit among those with AF. Evidence is lacking that biventricular rather than AV resynchronization is an important mechanism for delivering the benefits of CRT.
John G F Cleland; Freidoon Keshavarzi; Pierpaolo Pellicori; Benjamin Dicken
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Publication Detail:
Type:  Journal Article     Date:  2013-08-21
Journal Detail:
Title:  Heart failure clinics     Volume:  9     ISSN:  1551-7136     ISO Abbreviation:  Heart Fail Clin     Publication Date:  2013 Oct 
Date Detail:
Created Date:  2013-09-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101231934     Medline TA:  Heart Fail Clin     Country:  United States    
Other Details:
Languages:  eng     Pagination:  461-74     Citation Subset:  IM    
Copyright Information:
Copyright © 2013 Elsevier Inc. All rights reserved.
Department of Cardiology, Castle Hill Hospital, Hull York Medical School, University of Hull, Kingston-upon-Hull HU6 5JQ, UK. Electronic address:
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