Document Detail

Case report: An unusual late relapse of Plasmodium vivax malaria.
MedLine Citation:
PMID:  12641405     Owner:  NLM     Status:  MEDLINE    
We observed an unusual case of Plasmodium vivax malaria who presented with an initial relapse four years after the primary infection. This occurred in Cameroon, where the patient, a 56-year-old priest, acquired a mild form of malaria and was treated with only chloroquine. Since he returned to Italy, he had not experienced any malaria-like symptoms, had not visited any other areas endemic for malaria, and had not received a blood transfusion. Blood smear microscopy confirmed the presence of Plasmodium spp. parasites, but unclear morphologic characteristics did not allow discrimination between P. vivax and P. ovale. A nested polymerase chain reaction-based molecular analysis identified P. vivax as the plasmodial species responsible. This case emphasizes the importance of taking into account the possibility of a very late initial relapse of P. vivax malaria and the relevant issues in terms of infection control.
Emanuele Durante Mangoni; Carlo Severini; Michela Menegon; Roberto Romi; Giuseppe Ruggiero; Giancarlo Majori
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of tropical medicine and hygiene     Volume:  68     ISSN:  0002-9637     ISO Abbreviation:  Am. J. Trop. Med. Hyg.     Publication Date:  2003 Feb 
Date Detail:
Created Date:  2003-03-18     Completed Date:  2003-03-27     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370507     Medline TA:  Am J Trop Med Hyg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  159-60     Citation Subset:  AIM; IM    
Dipartimento di Medicina Interna, Seconda Università di Napoli, Ospedale Gesù e Maria, Naples, Italy.
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MeSH Terms
Antimalarials / administration & dosage
Chloroquine / administration & dosage
DNA, Protozoan / genetics
Diagnosis, Differential
Drug Administration Schedule
Malaria, Vivax / diagnosis*,  drug therapy,  pathology
Middle Aged
Plasmodium vivax / genetics,  isolation & purification
Polymerase Chain Reaction
Primaquine / administration & dosage
Reg. No./Substance:
0/Antimalarials; 0/DNA, Protozoan; 54-05-7/Chloroquine; 90-34-6/Primaquine

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