Document Detail


Case report: a patient who developed an amoebic liver abscess during treatment with interferon.
MedLine Citation:
PMID:  9835326     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 65-year-old female received recombinant interferon (IFN) alpha-2b daily for the treatment of chronic hepatitis C. Fever (39 degrees C or higher) developed 14 days after the start of administration. Abdominal computed tomography suggested multiple liver abscesses, which had not been detected before IFN administration. An autopsy revealed an amoebic liver abscess. A subclinical infection of Entamoeba histolytica in this case developed into amoebic liver abscess during IFN administration.
Authors:
T Matsuo; H Shinzawa; K Sugahara; H Mitsuhashi; H Watanabe; T Abe; S Ohno; M Terashita; K Saito; T Saito; H Misawa; H Togashi; T Takahashi
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of gastroenterology and hepatology     Volume:  13     ISSN:  0815-9319     ISO Abbreviation:  J. Gastroenterol. Hepatol.     Publication Date:  1998 Oct 
Date Detail:
Created Date:  1999-02-09     Completed Date:  1999-02-09     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8607909     Medline TA:  J Gastroenterol Hepatol     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  1068-71     Citation Subset:  IM    
Affiliation:
Second Department of Internal Medicine, Yamagata University School of Medicine, Yamagata City, Japan.
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MeSH Terms
Descriptor/Qualifier:
Aged
Antiviral Agents / adverse effects*,  therapeutic use
Fatal Outcome
Female
Hepatitis C, Chronic / therapy*
Humans
Interferon Alfa-2b / adverse effects*,  therapeutic use
Liver Abscess, Amebic / diagnosis,  etiology*
Chemical
Reg. No./Substance:
0/Antiviral Agents; 99210-65-8/Interferon Alfa-2b

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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