| Case report: oxaprozin and fatal toxic epidermal necrolysis. | |
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MedLine Citation:
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PMID: 9710730 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We have presented a case of fulminating TEN with a fatal outcome. We believe there is strong probability that the TEN was caused by a propionic acid NSAID oxaprozin. This is the first reported case of TEN related to this particular agent. Toxic epidermal necrolysis has been reported with all types of NSAIDs. It appears from this case that switching from one class of nonsteroidal anti-inflammatories to another is not always without risk. Despite the class of nonsteroidal anti-inflammatory agent used, the possibility of systemic reaction cannot be excluded. |
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Authors:
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C N Paul; D W Voigt; K E Clyne; S L Hansen |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The Journal of burn care & rehabilitation Volume: 19 ISSN: 0273-8481 ISO Abbreviation: J Burn Care Rehabil Publication Date: 1998 Jul-Aug |
Date Detail:
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Created Date: 1998-10-19 Completed Date: 1998-10-19 Revised Date: 2006-08-15 |
Medline Journal Info:
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Nlm Unique ID: 8110188 Medline TA: J Burn Care Rehabil Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 321-3 Citation Subset: IM |
Affiliation:
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Burn and Wound Center, Saint Elizabeth Community Health Center, Lincoln, Nebraska 68510, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Anti-Inflammatory Agents, Non-Steroidal / adverse effects* Epidermal Necrolysis, Toxic / etiology* Fatal Outcome Female Humans Propionic Acids / adverse effects* |
| Chemical | |
Reg. No./Substance:
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0/Anti-Inflammatory Agents, Non-Steroidal; 0/Propionic Acids; 21256-18-8/oxaprozin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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