Document Detail


Case report: massive blood transfusion in a patient with immunoglobulin a deficiency undergoing cesarean delivery.
MedLine Citation:
PMID:  20357151     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Patients with immunoglobulin (Ig)A deficiency develop autoantibodies against IgA, which render them vulnerable to severe anaphylactic reactions when transfused with conventional blood or blood products containing IgA. In this report, we describe a patient with IgA deficiency and placenta accreta undergoing emergency cesarean delivery who required massive blood transfusion. We discuss the workup and treatment options in patients with known IgA deficiency.
Authors:
Christopher Steel; Sonia Vaida; Berend Mets
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Anesthesia and analgesia     Volume:  110     ISSN:  1526-7598     ISO Abbreviation:  Anesth. Analg.     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-04-01     Completed Date:  2010-04-23     Revised Date:  2010-05-28    
Medline Journal Info:
Nlm Unique ID:  1310650     Medline TA:  Anesth Analg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1088-90     Citation Subset:  AIM; IM    
Affiliation:
Department of Anesthesiology, Penn State Milton S. Hershey Medical Center, Hershey, PA 17033-0850, USA.
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MeSH Terms
Descriptor/Qualifier:
Adrenal Cortex Hormones / therapeutic use
Adult
Apgar Score
Blood Cell Count
Blood Transfusion*
Cesarean Section*
Diphenhydramine / therapeutic use
Female
Histamine H1 Antagonists / therapeutic use
Humans
IgA Deficiency / therapy*
Immunoglobulin A / analysis
Placenta Accreta / surgery
Pregnancy
Pregnancy Complications, Hematologic / therapy*
Chemical
Reg. No./Substance:
0/Adrenal Cortex Hormones; 0/Histamine H1 Antagonists; 0/Immunoglobulin A; 58-73-1/Diphenhydramine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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