Document Detail


Case report and literature review: HHV-6-associated meningoencephalitis in an immunocompetent adult.
MedLine Citation:
PMID:  19856546     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Human herpesvirus type 6 (HHV-6) has been well described as an agent of meningoencephalitis in post-haematopoietic stem cell transplantation patients, but is a rare cause of meningoencephalitis in immunocompetent adults. We report an immunocompetent adult with HHV-6-associated meningoencephalitis. The patient was an elderly diabetic man who presented with fever and confusion, with cerebrospinal fluid (CSF) pleocytosis. HHV-6 DNA was amplified from CSF by polymerase chain reaction. In our review of the medical literature we examine clinical presentations, laboratory findings, neuroimaging studies, treatments and clinical outcomes in immunocompetent patients with HHV-6 meningoencephalitis.
Authors:
Christopher H Trabue; Karen C Bloch; James W Myers; Jonathan P Moorman
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Herpes : the journal of the IHMF     Volume:  15     ISSN:  0969-7667     ISO Abbreviation:  Herpes     Publication Date:  2008 Nov 
Date Detail:
Created Date:  2009-10-27     Completed Date:  2009-12-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9801722     Medline TA:  Herpes     Country:  England    
Other Details:
Languages:  eng     Pagination:  33-5     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, James H Quillen College of Medicine, East Tennessee State University Medical Service, Johnson, TN 37614, USA. trabuec@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Aged
Diabetes Mellitus
Herpesvirus 6, Human / isolation & purification*
Humans
Immunocompetence*
Male
Meningoencephalitis / immunology,  virology*
Roseolovirus Infections / immunology,  virology*
Grant Support
ID/Acronym/Agency:
U50/CCU416123-09/CC/CDC HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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