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Case report: increased levothyroxine requirement in a patient with cryptic celiac-sprue disease.
MedLine Citation:
PMID:  15251601     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
An increased requirement for levothyroxine may be due to poor patient compliance, pregnancy, low potency levothyroxine preparations, interfering drugs and small intestinal disease. Data on thyroid hormone absorption in celiac sprue disease is limited to a single study involving four patients without thyroid disease, in which malabsorption of a single dose of radiolabeled levothyroxine was noted in three of the four subjects. Increased levothyroxine requirements have not been reported in hypothyroid patients with celiac sprue. Furthermore, cryptic celiac sprue has never been described to cause levothyroxine malabsorption. We report such a patient in whom cryptic celiac sprue was an important cause of levothyroxine malabsorption with increased thyroid hormone requirement.
Authors:
S K Grinspoon; G H Daniels
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists     Volume:  1     ISSN:  1530-891X     ISO Abbreviation:  Endocr Pract     Publication Date:    1995 Mar-Apr
Date Detail:
Created Date:  2004-07-14     Completed Date:  2005-02-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9607439     Medline TA:  Endocr Pract     Country:  United States    
Other Details:
Languages:  eng     Pagination:  88-90     Citation Subset:  -    
Affiliation:
Neuroendocrine Unit, Massachusetts General Hospital, Boston, MA 02114, USA.
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