| Case report: anesthetic management of acute fatty liver of pregnancy in the postpartum period. | |
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MedLine Citation:
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PMID: 20572409 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Acute fatty liver of pregnancy (AFLP) is a potentially fatal metabolic disorder that manifests during the third trimester. Early diagnosis, termination of pregnancy, and treatment of complications associated with AFLP significantly reduce maternal morbidity and mortality. While most cases of AFLP occur before delivery, some may occur after vaginal delivery. Anesthesia providers should have a high level of suspicion for AFLP in a patient with altered mental status and elevated liver function test results in the postpartum period. Anesthetic implications include early recognition of liver dysfunction and aggressive resuscitation and treatment of hypoglycemia, disseminated intravascular coagulopathy, and other associated complications and reduction or avoidance of medications with substantial hepatic metabolism. This is a case report describing the management of a woman with AFLP in whom acute liver failure rapidly developed after a vaginal delivery with epidural analgesia at a small overseas hospital. |
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Authors:
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Dennis Spence |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: AANA journal Volume: 78 ISSN: 0094-6354 ISO Abbreviation: AANA J Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-06-24 Completed Date: 2010-07-27 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0431420 Medline TA: AANA J Country: United States |
Other Details:
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Languages: eng Pagination: 223-8 Citation Subset: N |
Affiliation:
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Uniformed Services University of the Health Sciences, Nurse Anesthesia Program, Naval Medical Center San Diego, California, USA. dennis.spence@med.navy.mil |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Adult Anesthesia, Epidural* / adverse effects, nursing Anesthesia, Obstetrical* / adverse effects, nursing Critical Care Diagnosis, Differential Disseminated Intravascular Coagulation / etiology Early Diagnosis Fatty Liver* / diagnosis, etiology, therapy Female Humans Liver Failure, Acute / etiology Nurse Anesthetists Postnatal Care Pregnancy Puerperal Disorders* / diagnosis, etiology, therapy Resuscitation |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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