| Case report: Treatment failure using propanolol for treatment of focal subglottic hemangioma. | |
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MedLine Citation:
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PMID: 20846505 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Subglottic hemangioma is a rare, potentially life threatening tumor of infancy which poses serious treatment challenges. A number of medical and surgical therapies over the years have met with variable success, and are associated with numerous potential morbidities. A potential windfall in the management of infantile hemangiomas has arisen with the recent identification of propanolol as a highly efficacious and relatively safe new treatment modality. At least five reports in the literature have described the rapid, successful treatment of airway hemangiomas with oral propanolol. We describe the first reported treatment failure with propanolol for subglottic hemangioma in an infant who initially responded dramatically to the medication. |
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Authors:
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Karina T Canadas; Eric D Baum; Stella Lee; Samuel T Ostrower |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: International journal of pediatric otorhinolaryngology Volume: 74 ISSN: 1872-8464 ISO Abbreviation: Int. J. Pediatr. Otorhinolaryngol. Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-07-09 Completed Date: 2010-12-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8003603 Medline TA: Int J Pediatr Otorhinolaryngol Country: Ireland |
Other Details:
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Languages: eng Pagination: 956-8 Citation Subset: IM |
Affiliation:
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Department of Otolaryngology Head & Neck Surgery, Yale University School of Medicine, United States. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Female Follow-Up Studies Glottis / pathology Hemangioma / congenital, drug therapy*, pathology, surgery Humans Infant Laryngeal Neoplasms / congenital, drug therapy*, pathology, surgery Laryngoscopy / methods Laryngostenosis / diagnosis, etiology Neoplasm Recurrence, Local / pathology*, surgery Otorhinolaryngologic Surgical Procedures / methods* Propranolol / administration & dosage* Retreatment Risk Assessment Treatment Failure Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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525-66-6/Propranolol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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