Document Detail

Case report. Successful use of tenecteplase in massive pulmonary embolism with cardiopulmonary resuscitation immediately following tracheostomy.
MedLine Citation:
PMID:  16013664     Owner:  NLM     Status:  MEDLINE    
The use of thrombolytics for the treatment of massive pulmonary embolism with cardiopulmonary resuscitation is being controversially discussed. This is one of the first reports on the successful use of tenecteplase in a 59-year-old man who survived a massive pulmonary embolism after tracheostomy followed by a 30-minute cardiopulmonary resuscitation without cerebral damage. In such a dramatic clinical event, the immediate and simple use of this modern thrombolytic appears to be a justifiable last-resort treatment option until controlled studies in sufficiently sized patient populations will have proven or refuted its efficacy and safety.
W Abdulla; U Netter
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta anaesthesiologica Belgica     Volume:  56     ISSN:  0001-5164     ISO Abbreviation:  Acta Anaesthesiol Belg     Publication Date:  2005  
Date Detail:
Created Date:  2005-07-14     Completed Date:  2005-10-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0421022     Medline TA:  Acta Anaesthesiol Belg     Country:  Belgium    
Other Details:
Languages:  eng     Pagination:  179-82     Citation Subset:  IM    
Department of Anaesthesiology and Intensive Care Medicine, Klinikum Bernburg.
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MeSH Terms
Amyotrophic Lateral Sclerosis / complications
Cardiopulmonary Resuscitation*
Fibrinolytic Agents / therapeutic use*
Hemorrhage / complications
Intraoperative Complications / drug therapy*
Middle Aged
Pulmonary Embolism / drug therapy*
Respiratory Insufficiency
Tissue Plasminogen Activator / therapeutic use*
Reg. No./Substance:
0/Fibrinolytic Agents; 0/tenecteplase; EC Plasminogen Activator

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