Document Detail

Case of the month: A case of airway obstruction following tenecteplase administration.
MedLine Citation:
PMID:  16988319     Owner:  NLM     Status:  MEDLINE    
The value of thrombolysis in the treatment of acute myocardial infarction is well established. Haemorrhage into subcutaneous tissues is fortunately a rare complication of fibrinolytic administration. However, if as a result of trauma a haematoma develops within the neck following thrombolysis, it can lead to rapid airway compromise. This is the first reported case of tenecteplase administration leading to subcutaneous haemorrhage and consequent airway compromise. It is also the first reported case where the antecedent trauma was a jaw thrust.
L Kirkham; J Homewood; P Brook
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Emergency medicine journal : EMJ     Volume:  23     ISSN:  1472-0213     ISO Abbreviation:  Emerg Med J     Publication Date:  2006 Oct 
Date Detail:
Created Date:  2006-09-21     Completed Date:  2007-03-22     Revised Date:  2013-06-07    
Medline Journal Info:
Nlm Unique ID:  100963089     Medline TA:  Emerg Med J     Country:  England    
Other Details:
Languages:  eng     Pagination:  815-6     Citation Subset:  IM    
Department of Anaesthetics, Bristol Royal Infirmary, Bristol BS2 8HW, UK.
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MeSH Terms
Airway Obstruction / etiology*
Fibrinolytic Agents / adverse effects*
Hematoma / chemically induced*,  complications
Myocardial Infarction / drug therapy
Thrombolytic Therapy / adverse effects*
Tissue Plasminogen Activator / adverse effects*
Reg. No./Substance:
0/Fibrinolytic Agents; 0/tenecteplase; EC Plasminogen Activator

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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