Document Detail

Case-controlled comparison of a percutaneous collagen arteriotomy closure device versus manual compression after liver chemoembolization.
MedLine Citation:
PMID:  15758129     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To compare complications and outcomes between the use of the Duett collagen closure device after one or multiple deployments and manual compression in patients treated with transcatheter arterial chemoembolization (TACE) for primary or metastatic liver cancer. MATERIALS AND METHODS: A database of 214 patients who underwent a total of 426 TACE procedures between July 2001 and July 2003 was retrospectively analyzed with regard to the use of the Duett closure device to obtain hemostasis. The Duett device was used in 211 cases (121 patients), whereas manual compression was performed in 215 cases (93 patients). Primary endpoints included complications related to hemostasis, time to hemostasis (TTH), time to ambulation (TTA), and time to discharge (TTD). Risk factors were tested for correlation with complications (P < .05). Other endpoints included descriptive data regarding the Duett treatment group. RESULTS: Only minor complications were observed in both groups, without a statistically significant difference (P = .16). The mean TTH and TTA were significantly shorter (P < .0001) in the Duett group, whereas there was no difference in TTD between groups (P = .59). Reaccessing the same arterial site for separate procedures was not a significant risk factor for complications in the Duett group (P < .0001). CONCLUSION: The Duett closure device achieves similar safety and efficacy as manual compression in this distinct group of patients. In addition, this device can be safely and repetitively deployed at the arteriotomy site after each TACE procedure.
Kelvin Hong; Eleni Liapi; Christos S Georgiades; Jean-Francois H Geschwind
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of vascular and interventional radiology : JVIR     Volume:  16     ISSN:  1051-0443     ISO Abbreviation:  J Vasc Interv Radiol     Publication Date:  2005 Mar 
Date Detail:
Created Date:  2005-03-10     Completed Date:  2005-07-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9203369     Medline TA:  J Vasc Interv Radiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  339-45     Citation Subset:  IM    
Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Hospital, 600 North Wolfe Street, Blalock 545, Baltimore, Maryland 21287, USA.
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MeSH Terms
Analysis of Variance
Case-Control Studies
Chemoembolization, Therapeutic / instrumentation*
Chi-Square Distribution
Collagen / therapeutic use*
Equipment Design
Femoral Artery*
Hemostatic Techniques*
Leg / blood supply
Liver Neoplasms / pathology,  therapy*
Middle Aged
Punctures / instrumentation,  methods
Retrospective Studies
Risk Factors
Treatment Outcome
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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