Document Detail

Case clusters of leproid granulomas in foxhounds in New Zealand and Australia.
MedLine Citation:
PMID:  23140313     Owner:  NLM     Status:  Publisher    
Background -  Canine leproid granuloma (CLG) characteristically presents as single to multiple circumscribed dermal to subcutaneous nodules in haired skin. An unidentified mycobacterium is considered be the aetiological agent of this entity. Animals -  Several cases of canine leproid granulomas occurred in dogs in New Zealand during 2010 and 2011. Cases appeared in clusters, affecting multiple closely related foxhounds domiciled in the same kennels. All affected hounds recovered after topical and/or systemic antimicrobial therapy. Two similar outbreaks that occurred in foxhounds near Melbourne, Australia are also reported. Methods -  Cases were investigated using cytological, histological, microbiological and several molecular techniques. An environmental epidemiological study was also performed. Results -  A diagnosis of CLG was established in 11 dogs. Molecular identification of the causative agent confirmed that it was a mycobacterial species with 100% sequence homology within the amplified regions of the 16S rRNA gene and internal transcribed spacer (ITS1) with that found in association with similar infections from the USA, Brazil and Australia. Conclusion and clinical importance -  This report details the first occurrence of multiple cases of CLG occurring in in-contact dogs and the first proven case of CLG in dogs in New Zealand.
Bronwyn Smits; Richard Willis; Richard Malik; Virginia Studdert; Desmond M Collins; Pamela Kawakami; Duncan Graham; Janet A Fyfe
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Publication Detail:
Journal Detail:
Title:  Veterinary dermatology     Volume:  23     ISSN:  1365-3164     ISO Abbreviation:  Vet. Dermatol.     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-11-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9426187     Medline TA:  Vet Dermatol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  465-e88     Citation Subset:  -    
Copyright Information:
© 2012 The Authors. Veterinary Dermatology © 2012 ESVD and ACVD.
Gribbles Veterinary, 57 Sunshine Avenue, PO Box 195, Hamilton 3240, New Zealand Cambridge Veterinary Services, Wilson Street, PO Box 488, Cambridge 3450, New Zealand Centre for Veterinary Education, B22, The University of Sydney, NSW 2006, Australia School of Veterinary Science, University of Melbourne, Parkville, Victoria 3010, Australia AgResearch, NCBID Wallaceville, Ward Street, PO Box 40063, Upper Hutt 5014, New Zealand Animal Dermatology NZ, 12 Poynters Crescent, Nelson 7010, New Zealand Victorian Infectious Diseases Reference Laboratory, 10 Wreckyn Street, North Melbourne, Victoria 3051, Australia.
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