Document Detail

Case of adult T-cell leukemia with pulmonary involvement presenting as nodular shadows.
MedLine Citation:
PMID:  18419680     Owner:  NLM     Status:  MEDLINE    
A 60-year-old man with a diagnosis of smoldering adult T-cell leukemia (ATL) had been treated successfully for 4 years with psoralen and ultraviolet A therapy, gamma-interferon, oral etoposide and sobuzoxane. He subsequently developed rapidly-growing skin nodules over his entire body. Chest X-ray and thoracic computed tomography showed nodular shadows in the right lower lung field and nodules in both lower lung lobes. Despite combined chemotherapy, he died. Upon autopsy, numerous nodules were found in the bilateral lower lobes; microscopically, the nodules were diffusely infiltrated by ATL cells. Our review of the published work found only two previously reported cases of ATL with pulmonary involvement manifested as nodular shadows. Herein, we present details on the third case.
Kimitaka Oyama; Takuro Kanekura; Noriko Yoshii; Kentaro Yonekura; Kentaro Mera; Yoshikazu Hirayama; Yoshihisa Umekita; Hiroki Yoshida; Yoshiro Umemura; Tamotsu Kanzaki
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of dermatology     Volume:  35     ISSN:  0385-2407     ISO Abbreviation:  J. Dermatol.     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-04-18     Completed Date:  2008-07-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7600545     Medline TA:  J Dermatol     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  225-8     Citation Subset:  IM    
Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, Japan.
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MeSH Terms
Leukemia-Lymphoma, Adult T-Cell / radiography*,  therapy
Lung Neoplasms / radiography*,  therapy
Middle Aged
Skin Neoplasms / pathology*,  therapy

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