Document Detail


Case of adolescent with Paget-Schroetter syndrome and underlying thrombophilia due to an elevated lipoprotein (A).
MedLine Citation:
PMID:  16496286     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Upper extremity deep vein thrombosis (UEDVT) is a rare disorder in children and is most often associated with a central venous catheter (CVC), cancer, or an underlying thrombophilia. In adults, repetitive or strenuous upper extremity activity has been linked to mechanical compression of the thoracic outlet resulting in subclavian vein thrombosis, also known as Paget-Schroetter Syndrome (PSS). We present the case of a 14 year old female who was found to have an UEDVT consistent with PSS. On subsequent thrombophila screening, she was noted to have a significantly elevated lipoprotein (a) level of 83 (normal: <30 mg/dL). She underwent 3 months of anticoagulation therapy prior to her first rib resection and in follow-up was noted to have complete patency of her subclavian vein. This case illustrates the necessity for thrombophilia screening in the pediatric patient with UEDVT despite evidence of anatomic abnormality or mechanical venous compression.
Authors:
J Dintaman; C Watson; C J Fox; N Hoover; S Roberts; D L Gillespie
Related Documents :
904406 - Mucocutaneous lymph node syndrome: a new clinical entity.
507026 - Hypernephroma with nonmetastatic liver dysfunction (stauffer's syndrome) and hypercalce...
8665886 - Use of a laryngeal mask airway in an adult patient with the hunter syndrome.
2592946 - Syndrome of hemolysis, elevated liver enzymes, and low platelet count: report of 4 cases.
13728216 - A possible source of error in the diagnosis of phaeochromocytoma.
25116126 - The use of plasma exchange in hashimoto's encephalopathy: a case report and review of t...
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric blood & cancer     Volume:  49     ISSN:  1545-5009     ISO Abbreviation:  Pediatr Blood Cancer     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2007-10-22     Completed Date:  2007-12-06     Revised Date:  2009-01-12    
Medline Journal Info:
Nlm Unique ID:  101186624     Medline TA:  Pediatr Blood Cancer     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1036-8     Citation Subset:  IM    
Copyright Information:
2007 Wiley-Liss, Inc
Affiliation:
Department of Pediatrics, National Capital Consortium, Washington, District of Columbia, USA. jay.dintaman@na.amedd.army.mil
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adolescent
Anticoagulants / therapeutic use
Female
Follow-Up Studies
Humans
Kidney Failure / complications,  diagnosis,  therapy
Lipoprotein(a) / blood*
Syndrome
Thrombectomy / methods
Thrombophilia / complications*,  diagnosis,  drug therapy
Treatment Outcome
Upper Extremity / pathology
Venous Thrombosis / complications*,  diagnosis,  drug therapy
Chemical
Reg. No./Substance:
0/Anticoagulants; 0/Lipoprotein(a)

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Heart defects in X-linked heterotaxy: evidence for a genetic interaction of Zic3 with the nodal sign...
Next Document:  HLA association is different in children and adults with severe acquired aplastic anemia.