Document Detail


A case of well-tolerated and safe deferasirox administration during the first trimester of a spontaneous pregnancy in an advanced maternal age thalassemic patient.
MedLine Citation:
PMID:  21273766     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In this report, we present a case of a spontaneous pregnancy in a 42-year-old thalassemic woman referred to our Microcythemic Unit while she was on deferasirox (DFX) therapy. The patient had been on treatment with DFX since March 2008 and in March 2009 realized that she was pregnant at 12 weeks of gestation. The conception was spontaneous and the baby was born at full term without complications or malformations.
Authors:
Paolo Ricchi; Silvia Costantini; Anna Spasiano; Tiziana Di Matola; Patrizia Cinque; Luciano Prossomariti
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2011-01-27
Journal Detail:
Title:  Acta haematologica     Volume:  125     ISSN:  1421-9662     ISO Abbreviation:  Acta Haematol.     Publication Date:  2011  
Date Detail:
Created Date:  2011-05-17     Completed Date:  2011-08-02     Revised Date:  2013-06-03    
Medline Journal Info:
Nlm Unique ID:  0141053     Medline TA:  Acta Haematol     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  222-4     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 S. Karger AG, Basel.
Affiliation:
Oncohematologic Department, Microcythemic Center 'A. Mastrobuoni', A. Cardarelli Hospital, Naples, Italy. pabloricchi@libero.it
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MeSH Terms
Descriptor/Qualifier:
Administration, Oral
Adult
Benzoates / administration & dosage,  therapeutic use*
Female
Humans
Iron Chelating Agents / therapeutic use*
Maternal Age
Pregnancy
Pregnancy Complications, Hematologic / drug therapy*
Pregnancy Outcome
Pregnancy Trimester, First
Triazoles / administration & dosage,  therapeutic use*
beta-Thalassemia / drug therapy*
Chemical
Reg. No./Substance:
0/Benzoates; 0/Iron Chelating Agents; 0/Triazoles; V8G4MOF2V9/deferasirox

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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