Document Detail


A Case of Sudden Infant Death Due to a Primary Cardiac Sarcoma.
MedLine Citation:
PMID:  22564127     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
  The case reported herein concerns the unexpected death of a 3-month-old female newborn who suddenly collapsed in her mother's arms and was dead on arrival at the hospital. The clinical histories of the baby and her parents were negative for symptoms or signs of illness, even those of cardiovascular origin. Furthermore, no clinical appearance of a pathologic status was noted by pediatricians after the birth until the last emergency recovery. The autopsy excluded external and internal signs of violence but revealed a large primary cardiac tumor arising from the free wall of the left ventricle, which had totally invaded the heart causing mitral valve deformation. Histological examination showed a low-grade sarcoma that completely infiltrated the myocardial tissue. The pathogenesis of this sudden infant death was postulated as being owing to a fatal ventricular fibrillation combined with a tumor-related restrictive cardiomyopathy obstructing left ventricular filling.
Authors:
Fidelia Cascini; Francesca Longo; Dante Parenti; Arnaldo Capelli
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-5-4
Journal Detail:
Title:  Journal of forensic sciences     Volume:  -     ISSN:  1556-4029     ISO Abbreviation:  -     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-5-8     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375370     Medline TA:  J Forensic Sci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2012 American Academy of Forensic Sciences.
Affiliation:
Institute of Legal Medicine, Università Cattolica del Sacro Cuore, Largo F. Vito 1, 00168 Roma, Italy. Department of Neonatology, 'Cristo Re' Hospital, Via delle Calasanziane 25 , 00167 Roma, Italy. Institute of Pathology, Università Cattolica del Sacro Cuore, Largo F. Vito 1, 00168 Roma, Italy.
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