Document Detail


A Case of ST-elevated myocardial infarction resulting from obstructive intramural coronary amyloidosis.
MedLine Citation:
PMID:  20379049     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 49-year-old man presenting with ST-elevated myocardial infarction was brought to our emergency department with AL amyloidosis. Baseline coronary angiography showed no significant stenosis of the epicardial coronary arteries, however, coronary artery angiography in response to acetylcholine and coronary flow reserve in response to papaverine were abnormal, which suggested impairment of vascular endothelial function. Myocardial biopsy revealed amyloid deposition exclusively in intramural coronary arteries. Early amyloidosis without myocardial involvement can produce acute coronary syndrome through the combination of spastic epicardial coronary arteries and obstruction of the intramural coronary arteries. In the management of certain patients with acute coronary syndrome, the possibility of cardiac amyliodosis should be taken into consideration.
Authors:
Katsura Soma; Masataka Takizawa; Hiroki Uozumi; Naoshi Kobayakawa; Tamiko Takemura; Junichi Shiraishi; Teruhiko Aoyagi
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  International heart journal     Volume:  51     ISSN:  1349-2365     ISO Abbreviation:  Int Heart J     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-04-09     Completed Date:  2010-05-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101244240     Medline TA:  Int Heart J     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  134-6     Citation Subset:  IM    
Affiliation:
Department of Cardiovascular Medicine, Japanese Red Cross Medical Center, Shibuya-ku, Tokyo, Japan.
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MeSH Terms
Descriptor/Qualifier:
Amyloidosis / complications,  pathology*,  physiopathology
Coronary Occlusion / etiology*,  pathology,  physiopathology
Humans
Male
Middle Aged
Myocardial Infarction / etiology*,  pathology,  physiopathology*

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