Document Detail


[A Case Report of Severe Hypo-Phosphatemia Due to Paraneoplastic Syndrome Followed by Severe Hyper-Phosphatemia Due to Tumor Lysis Syndrome after CHOP Chemotherapy].
MedLine Citation:
PMID:  22333654     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
A 51-year-old man who underwent umbilical cord blood transplantation for acute lymphoblastic leukemia with a Philadelphia chromosome in April 2006 achieved complete remission. In June 2008, progressive renal dysfunction and melena emerged and the patient was diagnosed with B-cell-type malignant lymphoma. He presented with severe hypo-phosphate- mia(0. 1m g/dL)due to paraneoplastic syndrome, simultaneously. Because the development of tumor lysis syndrome followed by hyper-phophatemia was feared to occur after CHOP chemotherapy, we discontinued the adjustment of serum phosphorus. The serum phosphorus level was elevated to 11.6mg/dL after 3 days and decreased to 3. 8mg/dL after 5 days. We must be careful regarding hyper-phosphatemia and phosphorus adjustment even in patients with severe hypo-phosphatemia that is due to paraneoplastic syndrome.
Authors:
Tadaaki Ito; Yumiko Uchida; Shinsuke Takagi; Naoyuki Uchida; Shuichi Taniguchi; Masahiro Hayashi
Publication Detail:
Type:  English Abstract; Journal Article    
Journal Detail:
Title:  Gan to kagaku ryoho. Cancer & chemotherapy     Volume:  39     ISSN:  0385-0684     ISO Abbreviation:  Gan To Kagaku Ryoho     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-02-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7810034     Medline TA:  Gan To Kagaku Ryoho     Country:  Japan    
Other Details:
Languages:  jpn     Pagination:  325-8     Citation Subset:  IM    
Affiliation:
Dept. of Pharmacy, Toranomon Hospital.
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