Document Detail


Case Report: Pregnancy in a patient with recurrent glioblastoma.
MedLine Citation:
PMID:  25075279     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
We report the case of a woman with relapsed glioblastoma multiforme (GBM) who recently gave birth. She announced her pregnancy shortly after the sixth cycle of a dense regimen of temozolomide, prescribed for treating the first recurrence of glioblastoma. Three years ago, in April 2008, she had undergone gross total resection of a glioblastoma multiforme in the postcentral region of the right hemisphere and had subsequently received treatment according to the actual standard therapy consisting of radiotherapy up to 60 Gy with concomitant and adjuvant temozolomide. The complete amount of temozolomide given before this pregnancy was 20.9 mg/m (2). Nevertheless, she delivered a 1890 g child by caesarean section in the 32/6 week of pregnancy. The child showed no anomalies and is developing normally under close surveillance by paediatricians.
Authors:
Birgit Flechl; Marco Ronald Hassler; Gerhard Kopetzky; Peter Balcke; Christine Kurz; Christine Marosi
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Publication Detail:
Type:  Journal Article     Date:  2013-11-15
Journal Detail:
Title:  F1000Research     Volume:  2     ISSN:  2046-1402     ISO Abbreviation:  F1000Res     Publication Date:  2013  
Date Detail:
Created Date:  2014-07-30     Completed Date:  2014-07-30     Revised Date:  2014-08-04    
Medline Journal Info:
Nlm Unique ID:  101594320     Medline TA:  F1000Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  246     Citation Subset:  -    
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