Document Detail


Case report: Fibroxanthoma: a complication of a biodegradable screw.
MedLine Citation:
PMID:  19936858     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Biodegradable interference screws in anterior cruciate ligament (ACL) reconstruction have gained popularity because of their similar or superior fixation strength in comparison to metallic interference screws and because they do not cause imaging artifacts and do not need to be removed.
CASE DESCRIPTION: We report the case of a 23-year-old man who presented with slowly progressive firm swelling of 2 months' duration at the site of the tibial tunnel 3 years after ACL reconstruction using a biodegradable interference screw. After curettage and débridement, the material was sent for histopathologic examination, which was reported as a fibroxanthoma.
LITERATURE REVIEW: Reported complications are osteolysis around the screw, allergic reaction, sterile abscess formation, ganglion cyst formation, and intraarticular migration. A fibroxanthoma consists of fibroblasts and mononuclear or multinucleated cells with large lipid-filled histiocytes (foam cells). The cells are negative for S-100 and keratin and positive for anti-human macrophage marker HAM-56.
PURPOSES AND CLINICAL RELEVANCE: Use of biodegradable screws is associated with high healing rates and low complication rates; however, awareness of their potential complications may help in early recognition and prevention of associated morbidity.
Authors:
Mir Sadat-Ali; Quamar Azzam; Mohammed Bluwi; Abdallah S Al-Umran
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-11-21
Journal Detail:
Title:  Clinical orthopaedics and related research     Volume:  468     ISSN:  1528-1132     ISO Abbreviation:  Clin. Orthop. Relat. Res.     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-02     Completed Date:  2010-07-20     Revised Date:  2013-05-31    
Medline Journal Info:
Nlm Unique ID:  0075674     Medline TA:  Clin Orthop Relat Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2284-7     Citation Subset:  AIM; IM    
Affiliation:
The University Department of Orthopaedic Surgery, College of Medicine, King Faisal University, Dammam, Saudi Arabia. drsadat@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Absorbable Implants / adverse effects*
Adult
Anterior Cruciate Ligament / surgery
Antibodies, Monoclonal / analysis
Bone Neoplasms / chemistry,  pathology*,  surgery
Bone Screws / adverse effects*
Curettage
Debridement
Histiocytes / chemistry,  pathology
Histiocytoma, Benign Fibrous / chemistry,  pathology*,  surgery
Humans
Macrophages / chemistry,  pathology
Male
Prosthesis Failure
Tibia / pathology*,  surgery
Chemical
Reg. No./Substance:
0/Antibodies, Monoclonal; 0/HAM-56 antibody
Comments/Corrections
Comment In:
Clin Orthop Relat Res. 2011 Jan;469(1):300-1; author reply 302   [PMID:  20878555 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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