Document Detail

A Case of Paradoxical Embolic ST-Segment Elevation Myocardial Infarction Triggered by Sleep Apnea.
MedLine Citation:
PMID:  22821099     Owner:  NLM     Status:  In-Data-Review    
This report describes an obese 39-year-old man who experienced ST-segment elevation myocardial infarction with total thrombotic occlusion of the right coronary artery. Culprit vessel flow was improved by aspiration. Data suggested that myocardial infarction had resulted from paradoxical embolus via a patent foramen ovale triggered by the Mueller maneuver, which had induced negative intrathoracic pressure following an acute increase of right-heart volume in the context of obesity and sleep-disordered breathing (SDB). Obesity is increasing among younger populations and it represents a risk for SDB and thrombosis. Thus, this mechanism should be included within the differential diagnosis for myocardial infarction in young patients.
Shingo Kujime; Hidehiko Hara; Yoshinari Enomoto; Hisao Yoshikawa; Hideki Itaya; Mahito Noro; Makoto Suzuki; Masato Nakamura; Kaoru Sugi
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Publication Detail:
Type:  Journal Article     Date:  2012-07-15
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  51     ISSN:  1349-7235     ISO Abbreviation:  Intern. Med.     Publication Date:  2012  
Date Detail:
Created Date:  2012-07-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1851-5     Citation Subset:  IM    
Division of Cardiovascular Medicine, Toho University Ohashi Medical Center, Japan.
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