Document Detail

A Case of Light Chain Deposition Disease (LCDD) in a Young Patient.
MedLine Citation:
PMID:  23024482     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Light chain disease is a variant of multiple myeloma in which the malignant population of marrow cells produces free monoclonal light chains but no heavy chain or complete immunoglobulin. The monoclonal light chains are small enough to be freely filtered by the kidneys and become Bence-Jones protein. Light chain disease comprises about 18% of multiple myeloma patients. Here we present a case report of a 38-year-old man who initially presented with complaints of pain in back and low grade fever off and on. He was found to have collapse of D9 and D12 vertebrae along with ascites and right pleural effusion and massive proteinuria. Multiple myeloma was considered as a differential diagnosis based on the investigations but eventually the patient was lost to follow up. This case is reported here as the light chain variant of multiple myeloma leading to deposition disease is less commonly reported and presents considerable difficulties in diagnosis.
Mala Mahto; Sudhesna Mohapatra; G Sumitra; Smita Kaushik; T K Mishra; Alpana Saxena
Publication Detail:
Type:  Journal Article     Date:  2011-01-11
Journal Detail:
Title:  Indian journal of clinical biochemistry : IJCB     Volume:  26     ISSN:  0974-0422     ISO Abbreviation:  Indian J Clin Biochem     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2012-10-01     Completed Date:  2012-10-02     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  8708303     Medline TA:  Indian J Clin Biochem     Country:  India    
Other Details:
Languages:  eng     Pagination:  420-2     Citation Subset:  -    
Department of Biochemistry, Maulana Azad Medical College, New Delhi, 110002 India.
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