Document Detail


A Case of Intravascular Large B-cell Lymphoma (IVLBCL) with no Abnormal Findings on Chest Computed Tomography Diagnosed by Random Transbronchial Lung Biopsy.
MedLine Citation:
PMID:  21173545     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
A 58-year-old woman was admitted with refractory fever despite receiving broad-spectrum antibiotics. She had hypoxemia, severe anemia, elevated levels of serum lactic dehydrogenase and soluble interleukin-2 receptor, and a positive direct Coombs test, which suggested an underlying autoimmune hemolytic anemia (AIHA). Chest computed tomography (CT) showed no abnormal findings, but she had hypoxia, and her alveolar-arterial oxygen difference (A-aDO(2)) was increased. A random transbronchial lung biopsy (TBLB) was performed, and pathological analysis showed massive proliferation of tumor cells in the lumina of the small vessels. Intravascular large B-cell lymphoma (IVLBCL) was diagnosed, and her general status improved after chemotherapy.
Authors:
Norihito Kaku; Masafumi Seki; Seiji Doi; Tomayoshi Hayashi; Daisuke Imanishi; Yoshifumi Imamura; Shintaro Kurihara; Taiga Miyazaki; Koichi Izumikawa; Hiroshi Kakeya; Yoshihiro Yamamoto; Katsunori Yanagihara; Takayoshi Tashiro; Shigeru Kohno
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Publication Detail:
Type:  Journal Article     Date:  2010-12-15
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  49     ISSN:  1349-7235     ISO Abbreviation:  Intern. Med.     Publication Date:  2010  
Date Detail:
Created Date:  2010-12-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  2697-701     Citation Subset:  IM    
Affiliation:
The Second Department of Internal Medicine, Nagasaki University Hospital.
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