| A case of complete hydatidiform mole with coexistent fetus: conclusive diagnosis of androgenesis of the molar placenta by variation of paternal acrocentric short arms. | |
| | |
MedLine Citation:
|
PMID: 19544248 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
A twin pregnancy consisting of complete hydatidiform mole with coexisting fetus is an extremely rare condition. Recent advances in obstetric ultrasonography and cytogenetic analysis have made the prenatal diagnosis of this rare pregnancy possible. Recent literature advocating DNA polymorphism analysis being required for the accurate diagnosis of complete hydatidiform mole with coexisting fetus is discussed. We present a case of complete hydatidiform mole with coexisting fetus terminated at 16 weeks' gestation. After successful termination of the pregnancy with intravaginal gemeprost, androgenesis of the molar placenta was proven by karyotyping analysis only, without DNA polymorphism analysis, because the short arm of chromosome 21 of the paternal allele had the normal variant satellite. To our knowledge, this is the first case report of complete hydatidiform mole with coexisting fetus diagnosed by variation of the acrocentric short arms, followed by termination with intravaginal gemeprost. We describe the clinical course of our case and review some literature concerning complete hydatidiform mole with coexisting fetus. |
| | |
Authors:
|
Shinsuke Koyama; Takuji Tomimatsu; Kenjiro Sawada; Takeshi Kanagawa; Aki Isobe; Yukiko Kinugasa; Tateki Tsutsui; Tadashi Kimura |
Related Documents
:
|
17376048 - Is aperistalsis with complete lower esophageal sphincter relaxation an early stage of c... 7590698 - Localized endometrial proliferations associated with pregnancy: clinical and histopatho... 17879828 - Simplifying the preevacuation testing strategy for patients with molar pregnancy. 3730328 - The medical value of examining tissue from therapeutic abortions: an analysis of 13,477... 21481058 - Contraceptive vaccines targeting factors involved in establishment of pregnancy. 21388678 - Villous trophoblast abnormalities in extremely preterm deliveries with elevated second ... |
Publication Detail:
|
Type: Case Reports; Journal Article Date: 2009-06-19 |
Journal Detail:
|
Title: American journal of perinatology Volume: 27 ISSN: 1098-8785 ISO Abbreviation: Am J Perinatol Publication Date: 2010 Feb |
Date Detail:
|
Created Date: 2010-01-22 Completed Date: 2010-04-06 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8405212 Medline TA: Am J Perinatol Country: United States |
Other Details:
|
Languages: eng Pagination: 143-9 Citation Subset: IM |
Copyright Information:
|
Thieme Medical Publishers. |
Affiliation:
|
Division of Obstetrics and Gynecology, Department of Specific Organ Regulation, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan. skoyama@gyne.med.osaka-u.ac.jp |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Abortifacient Agents, Nonsteroidal
/
administration & dosage Abortion, Induced Adult Alprostadil / administration & dosage, analogs & derivatives Chromosome Aberrations* Chromosomes, Human, Pair 21 / genetics* Female Fetus / embryology* Genetic Variation Humans Hydatidiform Mole / diagnosis* Karyotyping Pregnancy Pregnancy Trimester, First Ultrasonography, Prenatal Uterine Neoplasms / diagnosis* |
| Chemical | |
Reg. No./Substance:
|
0/Abortifacient Agents, Nonsteroidal; 64318-79-2/gemeprost; 745-65-3/Alprostadil |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Results of Nasal Screening for Methicillin-Resistant Staphylococcus aureus during a Neonatal Intensi...
Next Document: Antenatal corticosteroids prior to 24 weeks' gestation and neonatal outcome of extremely low birth w...