Document Detail

Carvedilol-induced changes in cardiac diastolic performance in a patient with isolated noncompaction of the myocardium.
MedLine Citation:
PMID:  12211534     Owner:  NLM     Status:  MEDLINE    
Isolated ventricular noncompaction (IVNC) is an unusual congenital heart disease. The morphological features are trabeculations and intertrabecular recesses within the left ventricle. Important clinical considerations include the high mortality due to depressed cardiac function, and the instance of ventricular arrhythmia and systemic embolism. One of reasons for the high mortality is that there is still no effective therapy with the exception of the recommendation for anticoagulation therapy to prevent embolisms. Hence, we describe a 29-year-old man with IVNC presenting with chronic heart failure. Careful up-titration of carvedilol in this patient changed the parameters of cardiac diastolic performance
Tomohiro Harada; Eiji Ohtaki; Koichi Kitahara; Tetsuya Sumiyoshi; Saichi Hosoda
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  41     ISSN:  0918-2918     ISO Abbreviation:  Intern. Med.     Publication Date:  2002 Aug 
Date Detail:
Created Date:  2002-09-04     Completed Date:  2003-04-07     Revised Date:  2013-05-28    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  642-7     Citation Subset:  IM    
Department of Cardiology, Sakakibara Heart Institute, Tokyo.
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MeSH Terms
Adrenergic beta-Antagonists / administration & dosage,  therapeutic use*
Carbazoles / administration & dosage,  therapeutic use*
Cardiomyopathies / drug therapy*,  physiopathology,  ultrasonography
Diastole / drug effects
Echocardiography, Doppler
Exercise Test
Heart Defects, Congenital / drug therapy*,  physiopathology,  ultrasonography
Heart Failure / drug therapy,  physiopathology,  ultrasonography
Hemodynamics / drug effects
Neuropeptides / blood
Propanolamines / administration & dosage,  therapeutic use*
Reg. No./Substance:
0/Adrenergic beta-Antagonists; 0/Carbazoles; 0/Neuropeptides; 0/Propanolamines; 0K47UL67F2/carvedilol
Comment In:
Intern Med. 2002 Aug;41(8):601-2   [PMID:  12211522 ]
Intern Med. 2002 Aug;41(8):603-4   [PMID:  12211523 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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