| Cartilage histomorphometry. | |
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MedLine Citation:
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PMID: 17951657 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In rheumatology and joint research, as in other fields, a purely descriptional appqoach to morphology cannot satisfy the exactions of modern clinical medicine. Investigators now appreciate the need to gauge pathological changes and their response to treatment by quantifying susceptible structural parameters. But the desired information respecting three-dimensional structures must be gleaned from either actual or virtual two-dimensional sections through the tissue. This information can be obtained only if the laws governing stereology are respected. In this chapter, the stereological principles that must be applied, and the practical methods that have been devised, to yield unbiased estimates of the most commonly determined structural parameters, namely, volume, surface area and number, are summarized. |
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Authors:
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Ernst B Hunziker |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Methods in molecular medicine Volume: 135 ISSN: 1543-1894 ISO Abbreviation: Methods Mol. Med. Publication Date: 2007 |
Date Detail:
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Created Date: 2007-10-22 Completed Date: 2007-12-06 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101123138 Medline TA: Methods Mol Med Country: United States |
Other Details:
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Languages: eng Pagination: 147-66 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cartilage / anatomy & histology* Humans Imaging, Three-Dimensional / methods*, statistics & numerical data Models, Anatomic |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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