Document Detail


The Carpentier-Edwards pericardial bioprosthesis: clinical experience with 600 patients.
MedLine Citation:
PMID:  7646176     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Carpentier-Edwards pericardial bioprostheses were implanted in 600 patients: 416 aortic valve replacement, 115 mitral valve replacement, 6 isolated tricuspid, and 63 multiple valve replacements. The survival rates were 70% at 10 years after aortic valve replacement, 62% 8 years after mitral valve replacement, and 57% at 8 years with multiple valve replacement. Overall, 69 patients suffered one or more valve-related complications. The 10-year freedom rates from embolism were 91% (aortic valve replacement), 92% (mitral valve replacement), and 89% (multiple valve replacement), and those from endocarditis were 95%, 93%, and 85%, respectively. In 18 of the 35 patients, reoperation was due to primary valve dysfunction. Freedom from primary dysfunction was 87% at 10 years with aortic valve replacement, and at 8 years, it was 79% with mitral valve replacement and 77% with multiple valve replacement. A direct correlation was found between freedom from valve dysfunction and age of the patient at operation, with a 10-year-free rate of 90% among patients older than 59 years. This bioprosthesis has an excellent durability up to 10 years in the aortic position. More data regarding its long-term durability in the mitral position are needed. It is currently our valve substitute of choice when a bioprosthesis is indicated.
Authors:
L C Pelletier; M Carrier; Y Leclerc; I Dyrda
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  60     ISSN:  0003-4975     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  1995 Aug 
Date Detail:
Created Date:  1995-09-20     Completed Date:  1995-09-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  S297-302     Citation Subset:  AIM; IM    
Affiliation:
Department of Surgery, Montreal Heart Institute, Quebec, Canada.
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MeSH Terms
Descriptor/Qualifier:
Actuarial Analysis
Adolescent
Adult
Age Factors
Aged
Aged, 80 and over
Aortic Valve / surgery
Bioprosthesis* / adverse effects,  mortality
Endocarditis / etiology
Female
Heart Valve Prosthesis* / adverse effects,  mortality
Humans
Male
Middle Aged
Mitral Valve / surgery
Prosthesis Failure
Reoperation
Survival Rate
Thromboembolism / etiology
Tricuspid Valve / surgery

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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