| Carotid thrombosis following neck irradiation. | |
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MedLine Citation:
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PMID: 2180869 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Therapeutic irradiation may accelerate atherosclerosis, increasing the risk of vascular stenosis or occlusion several to many years following radiation. However, intimal damage following irradiation may result earlier in thrombosis without stenosis. This report discusses three cases of carotid occlusion that occurred within 3 years of moderate dose irradiation. Angiographic studies showed that occlusion occurred in the absence of atherosclerotic stenosis. A review of the literature supports the conclusion that people who receive neck irradiation are at risk not only for the delayed development of diffuse atherosclerosis but also for thrombotic occlusion within months to several years. We suggest that patients who develop neurological symptoms or signs following neck irradiation, regardless of age, dose of radiation, or interval since radiation, should be evaluated for carotid or vertebral artery disease. |
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Authors:
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G K Call; P F Bray; W R Smoker; S S Buys; J K Hayes |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: International journal of radiation oncology, biology, physics Volume: 18 ISSN: 0360-3016 ISO Abbreviation: Int. J. Radiat. Oncol. Biol. Phys. Publication Date: 1990 Mar |
Date Detail:
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Created Date: 1990-05-10 Completed Date: 1990-05-10 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 7603616 Medline TA: Int J Radiat Oncol Biol Phys Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 635-40 Citation Subset: IM |
Affiliation:
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University of Utah School of Medicine, Salt Lake City, Utah 84132. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Carotid Artery Thrombosis / etiology* Female Head and Neck Neoplasms / radiotherapy* Hodgkin Disease / radiotherapy Humans Male Maxillary Sinus Neoplasms / radiotherapy Radiotherapy / adverse effects* Rhabdomyosarcoma / radiotherapy |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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