| Carotid-radial pulse wave velocity as a discriminator of intrinsic wall alterations during evaluation of endothelial function by flow-mediated dilatation. | |
| | |
MedLine Citation:
|
PMID: 22255817 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Flow-mediated dilatation (FMD) is the most accepted technique for the evaluation of endothelial function. However, it has been show a great inter-subject variability limiting its clinical use. Carotid-radial pulse wave velocity (PWVcr) was proposed as an alternative tool for the evaluation of endothelial function. At the present, there is no doubt that PWVcr reduces its values in response to reactive hyperemia test (RHT) in healthy subjects. Aims: a) to determine simultaneously the temporal profile of FMD, PWVcr and shear rate in response to RHT and b) to describe and analyze how subjects "FMD responders" or "non-responders" behave regards to PWVcr changes. Methods: 34 healthy young subjects were included. The PWVcr (strain gauge mechanotransducers), brachial diameter (B-Mode ultrasound and blood flow velocity (Doppler ultrasound) were measured before (baseline) the cuff was inflated and after its deflation (5 minutes). 10(th) percentiles FMD and PWVcr changes in the population were used for the definition of the subjects ("responders and non-responders"). Results: Changes in PWVcr, brachial arterial diameter and shear rate were evidenced after the cuff release (p<0.05). There were differences in the PWV and FMD temporal profiles. Within "FMD responders" there were "PWV responders and non-responders". Conclusion: Assessing RHT-related changes in PWVcr in the context of a FMD evaluation, could be useful as a discriminator of intrinsic wall alterations giving additional information of vascular dynamics. |
| | |
Authors:
|
J Torrado; D Bia; Y Zocalo; I Farro; F Farro; M Valero; R L Armentano |
Related Documents
:
|
3918547 - Venous and arterial blood gases during and after cardiopulmonary resuscitation in dogs. 241947 - Infantile gaucher's disease: glucocerebrosidase deficiency in peripheral blood leukocyt... 10483797 - Effect of pedal cadence on the accumulated oxygen deficit, maximal aerobic power and bl... 9887007 - Regulation of intracellular ph and blood flow in rat duodenal epithelium in vivo. 7158207 - The effects of lysine-vasopressin on hemodynamics during early post burn period in pigs. 19508277 - Brachial artery hyperemic blood flow velocities are related to carotid atherosclerosis. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference Volume: 2011 ISSN: 1557-170X ISO Abbreviation: Conf Proc IEEE Eng Med Biol Soc Publication Date: 2011 Aug |
Date Detail:
|
Created Date: 2012-01-18 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101243413 Medline TA: Conf Proc IEEE Eng Med Biol Soc Country: United States |
Other Details:
|
Languages: eng Pagination: 6458-61 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Age-related changes in reservoir and excess components of central aortic pressure in asymptomatic ad...
Next Document: Pulse arrival time is not an adequate surrogate for pulse transit time in terms of tracking diastoli...