| Carotid plaque, stroke pathogenesis, and CRP: treatment of ischemic stroke. | |
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MedLine Citation:
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PMID: 18416997 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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C-reactive protein (CRP), an inflammatory marker, has been identified as a likely predictor of the risk of a future stroke. In clinical settings, it has been consistently observed that higher concentrations of CRP are associated with larger brain infarcts and worst neurologic outcome. However, there is still controversy over the degree of risk conferred by elevated CRP concentrations. CRP, like many other hemostatic factors, is an acute-phase protein and, therefore, it is not always clear whether its association with cerebrovascular disease reflects its contribution to atherothrombosis, its acute-phase condition, or both. Whether a reduction of CRP levels could be beneficial to stroke patients remains to be clarified. More studies are needed before CRP becomes a routine part of the evaluation of stroke patients. |
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Authors:
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Jerzy Krupinski; Marta M Turu; Mark Slevin; José Martínez-González |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Current cardiology reports Volume: 10 ISSN: 1534-3170 ISO Abbreviation: Curr Cardiol Rep Publication Date: 2008 Feb |
Date Detail:
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Created Date: 2008-04-17 Completed Date: 2008-06-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100888969 Medline TA: Curr Cardiol Rep Country: United States |
Other Details:
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Languages: eng Pagination: 25-30 Citation Subset: IM |
Affiliation:
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Department of Neurology, Stroke Unit, Hospital Universitari de Bellvitge, Feixa Llarga s/n 08907 L'Hospitalet de Llobregat, Barcelona, Spain. krupinski@csub.scs.es |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Antihypertensive Agents
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therapeutic use Brain Ischemia / blood, drug therapy, physiopathology* C-Reactive Protein / metabolism* Carotid Arteries / pathology*, physiopathology Carotid Artery Diseases / blood, pathology*, physiopathology Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use Inflammation Platelet Aggregation Inhibitors / therapeutic use Risk Factors Stroke / blood, drug therapy, physiopathology* |
| Chemical | |
Reg. No./Substance:
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0/Antihypertensive Agents; 0/Hydroxymethylglutaryl-CoA Reductase Inhibitors; 0/Platelet Aggregation Inhibitors; 9007-41-4/C-Reactive Protein |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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