Document Detail


Carotid intima-media thickness: more than a research tool?
MedLine Citation:
PMID:  20306891     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Carotid intima-media thickness (CIMT) can be measured non-invasively by means of B-mode ultrasound. Carotid ultrasonography is readily available and enables the assessment of the full spectrum of the atherosclerotic process, from normal artery walls to arterial occlusion. In population studies, CIMT correlates with present and future cardiovascular disease (CVD). The method has been well validated in histological and epidemiological studies. Controlled clinical trials have shown the value of CIMT as a surrogate marker to evaluate established therapies and novel anti-atherosclerotic drugs. At present, CIMT is increasingly being used as a surrogate aimed at reducing CVD risk at an individual level. In this paper we discuss the potential usefulness of CIMT as a risk marker in clinical programmes of CVD prevention.
Authors:
Peter Verhamme; Flor Kerkhof; Ian Buysschaert; Ernst Rietzschel; Eric de Groot
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Acta cardiologica     Volume:  65     ISSN:  0001-5385     ISO Abbreviation:  Acta Cardiol     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-03-23     Completed Date:  2010-04-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370570     Medline TA:  Acta Cardiol     Country:  Belgium    
Other Details:
Languages:  eng     Pagination:  59-66     Citation Subset:  IM    
Affiliation:
Dept. of Vascular Medicine and Haemostasis, UZ Leuven Hospitals, Leuven, Belgium. Peter.Verhamme@uz.kuleuven.be
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MeSH Terms
Descriptor/Qualifier:
Atherosclerosis* / diagnosis,  epidemiology,  physiopathology
Biomedical Research / methods*
Carotid Arteries / pathology,  ultrasonography*
Disease Progression
Humans
Incidence
Prognosis
Risk Assessment / methods*
Severity of Illness Index
Tunica Intima / pathology,  ultrasonography*
Vasodilation / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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