| Carotid artery wall thickness and ischemic symptoms: evaluation using multi-detector-row CT angiography. | |
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MedLine Citation:
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PMID: 18404269 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The purpose of this study was to determine if carotid artery wall thickness (CAWT) studied by using multi-detector-row CT angiography (MDCTA) can be considered an effective parameter predictive of increased risk of stroke. A total of 217 patients were retrospectively studied by using MDCTA. In all patients CAWT was measured with an internal digital caliper. Continuous data were described as the mean value +/- standard deviation (SD), and they were compared with Student's t-test. Scatter plots to determine interobserver agreement were performed, and correlation coefficient was calculated with Pearson statistics. A P value <0.05 was considered to mean statistical significance. Measurements of the distal common CAWT ranged from 0.5 to 1.6 mm. In the patient group without stroke, average CAWT was 0.82 mm (0.22 SD), whereas in patient group with stroke it was 1.096 mm (0.21 SD). CAWT in patients without stroke showed statistical difference (P < 0.0001) when compared to patients with stroke. By using a threshold of 1 mm, an important statistical association between thick CAWT and stroke was found (P < 0.0001). In fact, patients with > or = 1 mm CAWT had stroke with an odds ratio of 8.16 when compared with patients with <1 mm CAWT. Resulting data suggested that an increased CAWT is an indicator for risk of stroke. This parameter should be considered in addition to other well-known risk factors such as diabetes, hypertension, smoking, and dyslipidemia. |
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Authors:
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Luca Saba; Roberto Sanfilippo; Luigi Pascalis; Roberto Montisci; Giancarlo Caddeo; Giorgio Mallarini |
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Publication Detail:
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Type: Evaluation Studies; Journal Article Date: 2008-04-11 |
Journal Detail:
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Title: European radiology Volume: 18 ISSN: 0938-7994 ISO Abbreviation: Eur Radiol Publication Date: 2008 Sep |
Date Detail:
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Created Date: 2008-08-05 Completed Date: 2009-01-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9114774 Medline TA: Eur Radiol Country: Germany |
Other Details:
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Languages: eng Pagination: 1962-71 Citation Subset: IM |
Affiliation:
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Department of Radiology, Azienda Ospedaliero Universitaria Polo di Monserrato, s.s. 554 Monserrato, Cagliari, 09045, Italy. lucasaba@tiscali.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Brain Ischemia / epidemiology*, radiography* Carotid Arteries / radiography* Cerebral Angiography / statistics & numerical data* Female Humans Italy / epidemiology Male Middle Aged Radiographic Image Interpretation, Computer-Assisted / methods Reproducibility of Results Risk Assessment / methods Risk Factors Sensitivity and Specificity Stroke / epidemiology*, radiography* Tomography, X-Ray Computed / statistics & numerical data* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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